Interpretation:Although Blade Runner is ostensibly an action film, it operates on multiple dramatic and narrative levels. It is indebted to film noir conventions: the femme fatale; protagonist-narration (removed in later versions); dark and shadowy cinematography; and the questionable moral outlook of the hero – in this case, extended to include reflections upon the nature of his own humanity. It is a literate science fiction film, thematically enfolding the philosophy of religion and moral implications of human mastery of genetic engineering in the context of classical Greek drama and hubris. It also draws on Biblical images, such as Noah's flood, and literary sources, such as Frankenstein. Linguistically, the theme of mortality is subtly reiterated in the chess game between Roy and Tyrell, based on the famous Immortal Game of 1851, though Scott has said that was coincidental -Wikipedia
I think this film set the stage for films such Gatica, Avatar, and other cloning Sci Fi films.